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Gene Expression Literature Summary
Assay
Age
In situ RNA (whole mount)
10.5 DPC

10 matching records from 10 references.

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Nkx2-5  NK2 homeobox 5   (Synonyms: Csx, Nkx-2.5, Nkx2.5, tinman)
Results  Reference
1J:87043 Huang C, Sheikh F, Hollander M, Cai C, Becker D, Chu PH, Evans S, Chen J, Embryonic atrial function is essential for mouse embryogenesis, cardiac morphogenesis and angiogenesis. Development. 2003 Dec;130(24):6111-9
1J:239155 Ikle JM, Tavares AL, King M, Ding H, Colombo S, Firulli BA, Firulli AB, Targoff KL, Yelon D, Clouthier DE, Nkx2.5 regulates endothelin converting enzyme-1 during pharyngeal arch patterning. Genesis. 2017 Mar;55(3)
1J:283041 Kim HS, Neugebauer J, McKnite A, Tilak A, Christian JL, BMP7 functions predominantly as a heterodimer with BMP2 or BMP4 during mammalian embryogenesis. Elife. 2019 Sep 30;8:e48872
1J:96337 Kokubo H, Miyagawa-Tomita S, Nakazawa M, Saga Y, Johnson RL, Mouse hesr1 and hesr2 genes are redundantly required to mediate Notch signaling in the developing cardiovascular system. Dev Biol. 2005 Feb 15;278(2):301-9
1*J:211545 Pu D, Du JL, Zhang J, Li XQ, Weng MJ, Liu YJ, Gao LZ, Xia S, Chen YQ, She Q, An economical and practical method for whole-mount in situ hybridization for mouse embryos and organs. Biotech Histochem. 2013 Jan;88(1):27-37
1J:289625 Shawer H, Aiyelaagbe E, Clowes C, Lean SC, Lu Y, Kadler KE, Kerby A, Dilworth MR, Hentges KE, Heazell AEP, A missense mutation of ErbB2 produces a novel mouse model of stillbirth associated with a cardiac abnormality but lacking abnormalities of placental structure. PLoS One. 2020;15(6):e0233007
1J:158984 Shimoji K, Yuasa S, Onizuka T, Hattori F, Tanaka T, Hara M, Ohno Y, Chen H, Egasgira T, Seki T, Yae K, Koshimizu U, Ogawa S, Fukuda K, G-CSF promotes the proliferation of developing cardiomyocytes in vivo and in derivation from ESCs and iPSCs. Cell Stem Cell. 2010 Mar 5;6(3):227-37
1J:175465 Urness LD, Bleyl SB, Wright TJ, Moon AM, Mansour SL, Redundant and dosage sensitive requirements for Fgf3 and Fgf10 in cardiovascular development. Dev Biol. 2011 Aug 15;356(2):383-97
1*J:180986 Wei Q, Condie BG, A focused in situ hybridization screen identifies candidate transcriptional regulators of thymic epithelial cell development and function. PLoS One. 2011;6(11):e26795
1J:124492 Zhu H, Wlodarczyk BJ, Scott M, Yu W, Merriweather M, Gelineau-van Waes J, Schwartz RJ, Finnell RH, Cardiovascular abnormalities in Folr1 knockout mice and folate rescue. Birth Defects Res A Clin Mol Teratol. 2007 Apr;79(4):257-68

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory